Role of 11C-choline PET/CT in parathyroid adenomas’ localization in patients with primary hyperparathyroidism

Background. Topical diagnosis of primary hyperparathyroidism (PHPT) remains an urgent problem due to the high incidence persistence and recurrence after surgical treatment. At preoperative stage, a search for parathyroid hormone hyperproduction source is performed using instrumental methods: ultrasound, scintigraphy glands (PTG) multislice computed tomography (MSCT). The cause PHPT parathyroidectomy may be multiple nature PTG lesions or their ectopic location. Additional methods visualization adenomas can used improve (PET/CT). Objective. To compare sensitivity specificity PET/CT with 11C-choline traditional techniques. Design methods. 16 patients were analyzed. All underwent US, subtraction 99mTc-technetril/99mTc-pertechnitate CT in 12 patients, respectively. was all patients. Imaging results’ coincidence two labeled as true one. Results. 94 %, CT, US — 75 69 % 63 11C-choline, 99mTc-technetril/99mTc-pertechnitate, 100 84 76 68 Conclusion. demonstrated best among become alternative diagnostics case negative inconvclusive results previous visualization.